The 49ers hammered the Raiders, 34-3, in November. And that victory has been sandwiched by what appear to be two convincing draft-day wins over their Bay Area rival. Advertisement Article continues below this ad On Thursday night, the Raiders were ...

The Indianapolis Colts lose to the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Score updates, highlights

On the Eagles' end, their weakness has been turnovers. Philadelphia has four games this year with two or more turnovers and the Eagles have gone 0-4 in those games. If any defense out there can take advantage of that, it's a Bills unit that has forced 20 turnovers this year, which ranks in the top eight in the NFL.

The 49ers got their ninth straight win and currently own the No. 2 seed in NFC, but they lost Dre Greenlaw (back) and Aaron Banks (knee). As of now, we don't for how long they will be out. The 49ers defense had another stinker, allowing the Raiders to gain ...