Like the human immune system, bacteria learn from past infections. CRISPR sequences—short snippets of DNA from previous viruses—guide destructive enzymes towards invading bacteriophages that express ...

Programmable CRISPR tools are turning stem cell biology into something closer to software engineering, shrinking ...

The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and its associated protein (Cas9) system is a genome-editing technology that holds the potential to alleviate multiple ...

Feng Zhang is a core institute member of the Broad Institute of MIT and Harvard, as well as an investigator at the McGovern Institute for Brain Research at MIT, co-director of the K. Lisa Yang and ...

Even without deep computational skills, scientists can use the CRISPRware program to quickly browse entire libraries of precomputed guide RNAs for six model organisms, zoom in on their gene or region ...

Scientists have made a significant breakthrough in agricultural biotechnology by using CRISPR/Cas9 to edit the potato genome, resulting in plants with increased resistance to both biotic and abiotic ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

Gene-editing techniques such as CRISPR-Cas9 have many uses in the area of food and agriculture. They can combat persistent drought and disease, and improve the colour and nutritional content of food ...

A powerful form of DNA-editing machinery discovered in bacteria might allow us to make much bigger changes to genomes than is currently possible with CRISPR-based techniques. However, it isn’t yet ...

UC and Broad have been involved in two interferences at the patent office. Interference No. 106,115 was the second interference between UC and Broad over patent rights to CRISPR-Cas9 technology in ...