In neurodegenerative diseases, microglia can help or harm the brain. In the October 3 Journal of Clinical Investigation, scientists led by Ilia Baskakov at the University of Maryland School of ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

Genetic neurodegenerative disorders like Tay-Sachs and Sandhoff disease currently have no effective treatments. A possible strategy is replacing affected cells with healthy ones in order to slow the ...

The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew.

“This is a paradigm shift,” says Donn Van Deren, PhD, postdoctoral research fellow at the University of Pennsylvania, who ...

More than 7 million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's ...

In healthy rodent brains, newborn neurons are constantly generated in the stem cell niche, known as the subventricular zone (SVZ). These cells might help to repair a brain that has been damaged by ...

Cedars-Sinai investigators have discovered a healing mechanism that could one day be harnessed to help treat patients with spinal cord injuries, stroke, and neurological conditions such as multiple ...

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at ...

The accumulation of pathological proteins is a hallmark of several neurodegenerative disorders, including Alzheimer’s disease, frontotemporal dementia and Parkinson’s disease. Proteins such as ...