Chris Vasile breaks down his favorite NFL picks against the spread for Week 18, including the Carolina Panthers and Baltimore Ravens.

All three SI panelists who submitted an upset pick for Week 17 cashed in. Matt Verderame correctly predicted the Houston Texans to take down the Los Angeles Cha

It's true the Titans secondary is occupied by practice squad players, but 13.5 points is a lot. I'm not calling for an upset, but don't forget that this Jaguars team has lost to the Titans in a critical Week 18 spot before.

RotoBaller's Week 18 NFL DFS value plays, sleeper picks, and tournament stacks for daily fantasy football on FanDuel, DraftKings, and Yahoo. Win big in DFS with our expert research and advice.

Florio’s pick: 49ers 27, Seahawks 24. Simms’s pick: Seahawks 28, 49ers 24. A meaningless game will have plenty of meaning, if Tampa wins on Saturday. Florio’s pick: Saints 23, Falcons 20. Simms’s pick: Falcons 24, Saints 17.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

Raiders 2. Jets 3. Cardinals 4. Titans 5. Giants 6. Browns 7. Commanders 8. Saints 9. Chiefs 10. Bengals 11. Dolphins 12. Cowboys 13. Falcons (traded first-round pick to Rams) 14. Ravens 15. Buccaneers 16.

SportsLine expert PropBetGuy, who is +1605 on his last 83 NFL player props, has revealed his top prop picks for Week 18