The 49ers have a strong chance to make the playoffs despite having the toughest remaining schedule. Here's what you need ...

San Francisco 49ers wide receiver Brandon Aiyuk has left the team, and his personal coach thinks he'll regret his decisions. San Francisco 49ers wide receiver Brandon Aiyuk has yet to play a snap this ...

The San Francisco 49ers got what they needed with the Seattle Seahawks win in Week 16, but one of their players learned a key lesson on a ...

The biggest takeaway from Thursday night's unprecedented two-point craziness was obvious: If you see a loose ball, pick it up.49ers coach Kyle Shanahan, ...

The footage has sparked growing concern about Aiyuk's well-being. One 49ers beat writer, Grant Cohn of Sports Illustrated, publicly appealed for someone —whether the team or Aiyuk's agent—to check in ...

San Francisco 49ers wide receiver Brandon Aiyuk has yet to play a snap this season and won't, after the team placed him on the reserve/left squad list. Aiyuk had been rehabbing the ACL and MCL ...

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San Francisco 49ers wide receiver Brandon Aiyuk hasn't been on the field this year, but he's been a frequent topic ...

The San Francisco 49ers defense is allowing 106.1 rushing yards per game heading into their Week 16 matchup against the Indianapolis Colts, ranking 12th in the NFL. They are also giving up 4.3 yards ...

The San Francisco 49ers will be without receiver Ricky Pearsall and cornerback Renardo Green on Monday night against the ...

The 49ers were a little more than one month removed from their Super Bowl loss when they made a controversial personnel ...

The San Francisco 49ers are preparing for their Week 16 contest against the Indianapolis Colts on Monday night at Lucas Oil Stadium in Indianapolis, Indiana. Because linebacker Erick Kendricks is on ...