Gene therapy - Mayo Clinic
Apr 23, 2024 · Gene therapy aims to fix a faulty gene or replace it with a healthy gene to try to cure disease or make the body better able to fight disease. It holds promise as a treatment for …
TERT expression may better predict meningioma behavior
Oct 7, 2025 · Researchers co-led by a Mayo Clinic Neurosurgery chair have demonstrated that telomerase reverse transcriptase (TERT) gene expression in meningiomas predicts earlier …
Chemotherapy for breast cancer - Mayo Clinic
Jan 10, 2025 · Gene expression profiling tests, such as Oncotype DX, EndoPredict and MammaPrint, may help predict the risk of recurrence and give your doctor an idea of how your …
Phase 1 clinical trial testing gene therapy treatment for knee ...
Oct 10, 2025 · Results demonstrate that injection of local gene therapy for knee joints is safe and achieves sustained, intra-articular concentrations of a therapeutic gene product.
HER2-positive breast cancer: What is it? - Mayo Clinic
Apr 9, 2024 · HER2-positive breast cancer tends to be more aggressive than other types of breast cancer. Treatments that target HER2 are very effective.
Publications - Andrew L. Folpe, M.D. - Mayo Clinic
Malignant melanotic schwannian tumor: a clinicopathologic, immunohistochemical, and gene expression profiling study of 40 cases, with a proposal for the reclassification of "melanotic …
Genomic testing expands options for melanoma staging
Nov 8, 2025 · A recent multicenter clinical trial based on research developed by Mayo Clinic experts provides valuable new insights into the management of early- and intermediate-stage …
Stem cell therapy for degenerative intervertebral disk disease: Q …
Jun 23, 2017 · In collaboration with orthopedic and neurosurgery researchers, we are examining the epigenetics in identifying gene expression profiles associated with disk degeneration. The …
Disease expression and familial transmission in Fuchs' endothelial ...
Jul 20, 2021 · For more information Xu TT, et al. Disease expression and familial transmission of Fuchs endothelial corneal dystrophy with and without CTG18.1 expansion. Investigative …
Publications - Jay W. Schneider, M.D., Ph.D. - Mayo Clinic
Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing. Proc Natl Acad Sci U S A. 2013 Oct 15; 110 (42):16850-5.